USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: APT_HUMAN USC-OGP 2-DE database:  APT_HUMAN APT_HUMAN General information about the entry View entry in simple text format Entry name APT_HUMAN Primary accession number P07741 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Adenine phosphoribosyltransferase; Short=APRT; EC=2.4.2.7;. Gene name Name=APRT Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1311: pI=5.46; Mw=22114 SPOT OGP-1314: pI=7.01; Mw=20959 Cross-references UniProtKB/Swiss-Prot P07741; APT_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name APT_HUMAN Primary accession number P07741 Secondary accession number(s) G5E9J2 Q3KP55 Q68DF9 Sequence was last modified on  January 23, 2007 (version 2) Annotations were last modified on  March 15, 2017 (version 193) Name and origin of the protein Description RecName: Full=Adenine phosphoribosyltransferase; Short=APRT; EC=2.4.2.7; Gene name Name=APRT Encoded on Name=APRT Keywords 3D-structure; Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Direct protein sequencing; Disease mutation; Glycosyltransferase; Phosphoprotein; Polymorphism; Purine salvage; Reference proteome; Transferase. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL Y00486; CAA68543.1; -; Genomic_DNA EMBL M16446; AAA51769.1; -; Genomic_DNA EMBL CR749423; CAH18261.1; -; mRNA EMBL AY306126; AAP45051.1; -; Genomic_DNA EMBL AC092384; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL CH471184; EAW66761.1; -; Genomic_DNA EMBL BC107151; AAI07152.1; -; mRNA EMBL BM550173; -; NOT_ANNOTATED_CDS; mRNA CCDS CCDS32511.1; -. [P07741-1]; . CCDS CCDS45546.1; -. [P07741-2]; . PIR S06232; RTHUA; . RefSeq NP_000476.1; NM_000485.2. [P07741-1]; . RefSeq NP_001025189.1; NM_001030018.1. [P07741-2]; . UniGene Hs.28914; -; . PDB 1OPU; Model; -; A=1-180 PDB 1ORE; X-ray; 2.10 A; A=1-180 PDB 1ZN7; X-ray; 1.83 A; A/B=1-180 PDB 1ZN8; X-ray; 1.76 A; A/B=2-180 PDB 1ZN9; X-ray; 2.05 A; A/B=1-180 PDB 4X44; X-ray; 2.05 A; A=1-180 PDB 4X45; X-ray; 1.75 A; A/B=1-180 PDBsum 1OPU; -; . PDBsum 1ORE; -; . PDBsum 1ZN7; -; . PDBsum 1ZN8; -; . PDBsum 1ZN9; -; . PDBsum 4X44; -; . PDBsum 4X45; -; . ProteinModelPortal P07741; -; . SMR P07741; -; . BioGrid 106849; 26; . IntAct P07741; 4; . MINT MINT-4999823; -; . STRING 9606.ENSP00000367615; -; . DrugBank DB03506; 9-Deazaadenine; . DrugBank DB00173; Adenine; . DrugBank DB00131; Adenosine monophosphate; . DrugBank DB01632; Alpha-Phosphoribosylpyrophosphoric Acid; . DrugBank DB04272; Citric Acid; . iPTMnet P07741; -; . PhosphoSitePlus P07741; -; . SwissPalm P07741; -; . BioMuta APRT; -; . DMDM 114074; -; . SWISS-2DPAGE P07741; -; . EPD P07741; -; . MaxQB P07741; -; . PaxDb P07741; -; . PeptideAtlas P07741; -; . PRIDE P07741; -; . TopDownProteomics P07741-1; -. [P07741-1]; . TopDownProteomics P07741-2; -. [P07741-2]; . Ensembl ENST00000378364; ENSP00000367615; ENSG00000198931. [P07741-1]; . Ensembl ENST00000426324; ENSP00000397007; ENSG00000198931. [P07741-2]; . GeneID 353; -; . KEGG hsa:353; -; . UCSC uc002flv.4; human. [P07741-1]; . CTD 353; -; . DisGeNET 353; -; . GeneCards APRT; -; . GeneReviews APRT; -; . HGNC HGNC:626; APRT; . HPA HPA026681; -; . MalaCards APRT; -; . MIM 102600; gene; . MIM 614723; phenotype; . neXtProt NX_P07741; -; . OpenTargets ENSG00000198931; -; . Orphanet 976; Adenine phosphoribosyltransferase deficiency; . PharmGKB PA24914; -; . eggNOG KOG1712; Eukaryota; . eggNOG COG0503; LUCA; . GeneTree ENSGT00390000017259; -; . HOGENOM HOG000036776; -; . HOVERGEN HBG003144; -; . InParanoid P07741; -; . KO K00759; -; . OMA VHALCAF; -; . OrthoDB EOG091G0XZC; -; . PhylomeDB P07741; -; . TreeFam TF300227; -; . Reactome R-HSA-6798695; Neutrophil degranulation; . Reactome R-HSA-74217; Purine salvage; . SABIO-RK P07741; -; . UniPathway UPA00588; UER00646; . ChiTaRS APRT; human; . EvolutionaryTrace P07741; -; . GeneWiki Adenine_phosphoribosyltransferase; -; . GenomeRNAi 353; -; . PRO PR:P07741; -; . Proteomes UP000005640; Chromosome 16; . Bgee ENSG00000198931; -; . CleanEx HS_APRT; -; . ExpressionAtlas P07741; baseline and differential; . Genevisible P07741; HS; . GO GO:0005737; C:cytoplasm; TAS:UniProtKB; . GO GO:0005829; C:cytosol; IDA:HPA; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005576; C:extracellular region; TAS:Reactome; . GO GO:0005654; C:nucleoplasm; IDA:HPA; . GO GO:0034774; C:secretory granule lumen; TAS:Reactome; . GO GO:0002055; F:adenine binding; IEA:Ensembl; . GO GO:0003999; F:adenine phosphoribosyltransferase activity; TAS:Reactome; . GO GO:0016208; F:AMP binding; IDA:MGI; . GO GO:0006168; P:adenine salvage; IEA:Ensembl; . GO GO:0044209; P:AMP salvage; IEA:UniProtKB-UniPathway; . GO GO:0032869; P:cellular response to insulin stimulus; IEA:Ensembl; . GO GO:0007625; P:grooming behavior; IEA:Ensembl; . GO GO:0007595; P:lactation; IEA:Ensembl; . GO GO:0043312; P:neutrophil degranulation; TAS:Reactome; . GO GO:0043101; P:purine-containing compound salvage; TAS:Reactome; . CDD cd06223; PRTases_typeI; 1; . Gene3D 3.40.50.2020; -; 1; . HAMAP MF_00004; Aden_phosphoribosyltr; 1; . InterPro IPR005764; Ade_phspho_trans; . InterPro IPR000836; PRibTrfase_dom; . InterPro IPR029057; PRTase-like; . Pfam PF00156; Pribosyltran; 1; . SUPFAM SSF53271; SSF53271; 1; . TIGRFAMs TIGR01090; apt; 1; . PROSITE PS00103; PUR_PYR_PR_TRANSFER; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

[Home]